Substance use is a serious concern in Indiana, though the state saw one of the biggest overdose death declines in the nation in 2023. Key figures:

• 34.2 drug overdose deaths per 100,000 people in 2023, down from 41 in 2022, according to CDC data.
• 2,190 overdose deaths in 2023, down from 2,666 in 2022, a drop of about 17%.
• One of the largest declines in the nation in 2023.
• Fentanyl accounts for about 66.6% of overdose deaths, with methamphetamine at about 30.7%.
• Fentanyl deaths decreased in 2023, while cocaine and methamphetamine deaths increased.
• The decline marked a reversal after years of increases.

Indiana’s crisis peaked in 2022 and turned sharply in 2023, with one of the steepest drops in the country. Fentanyl deaths fell, though cocaine and methamphetamine deaths continued to climb.

Indiana expanded Medicaid in 2015 through its Healthy Indiana Plan 2.0 (HIP 2.0), a conservative-style expansion. The state’s Division of Mental Health and Addiction (DMHA), under the Family and Social Services Administration, oversees substance use services. Of the 406 facilities listed below, 365 accept Medicaid.