Substance use is a concern in Minnesota, where fentanyl drives most overdose deaths, though the state’s rate sits below the national average and has been falling. Key figures:

• 23 drug overdose deaths per 100,000 people in 2023, below the national average.
• Fentanyl is involved in 92% of opioid-involved deaths, according to the Minnesota Department of Health.
• Fentanyl is involved in 62% of all overdose deaths.
• Overdose deaths declined about 8% from 2022 to 2023.
• Synthetic opioid (fentanyl) deaths fell 6%, from 949 to 892.
• Opioid deaths had increased 51% from 2020 to 2022 before the decline.

Minnesota’s crisis followed the national arc, with opioid deaths jumping 51% from 2020 to 2022 before the state finally saw declines in 2023. Fentanyl now dominates, involved in nearly all opioid deaths.

Minnesota expanded Medicaid in 2014 under the Affordable Care Act, extending coverage to adults up to 138% of the federal poverty level. The state’s Department of Human Services administers the program, which covers substance use disorder treatment. Of the 332 facilities listed below, 287 accept Medicaid.